Enthalpy-Sensing Microsystem Effective in Continuous Flow

A Microsystem for Monitoring Bacterial Quorum Sensing

Title of Dissertation: DESIGN, FABRICATION, AND TESTING OF A MICROSYSTEM FOR MONITORING BACTERIAL QUORUM SENSING Stephan Todorov Koev, Doctor of Philosophy, 2009 Directed By: Professor Reza Ghodssi, Department of Electrical and Computer Engineering Most pathogenic bacteria communicate with each other using signaling molecules. Their coordinated behavior, known as quorum sensing (QS), enables th...

Optical sensing of microsystem motion and performance $ @ a

Microsystems involve several fabrication technologies, but share the common trait of dimensions and motions measured in microns. Small feature sizes and deflections make the detection of microdevice motion particularly diftlcult. The rapid operating frequencies of many microactuators compound the detection problem. Effective feedback, control, and performance measurement of microactuators thus ...

Furrow geometry nnder surge and continuous flow

Selective High Efficiency In-flow Electroporation with Focused Electric Fields in a Microsystem

We present a new technique for delivery of macromolecules into biological cells in suspension by in-flow electroporation which achieves reproducible high delivery efficiency with excellent post-electroporation viability and enables delivery to selected cell types in mixtures. We detect cells via impedance change as they flow through a microfabricated sense-porate aperture and then electroporate...

Heterogeneous Hydrogenations in Continuous Flow

Catalytic heterogeneous hydrogenation processes arguably belong to the most valuable synthetic transformations known. Current batch reactor technology is not only time consuming and difficult to set up but also catalyst addition and filtration is hazardous. Because of the aromatic character of many substrates, hydrogenation often requires the use of significant hydrogen pressures in combination...